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Figure 7 | BMC Molecular Biology

Figure 7

From: Sex-biased transcription enhancement by a 5' tethered Gal4-MOF histone acetyltransferase fusion protein in Drosophila

Figure 7

Gal4-MOF co-localizes with MSL1 on polytene chromosomes. (A) Male (top) and female (bottom) larvae salivary gland nuclei that express Gal4-MOF and carry a UAS-lacZ transgene were stained with anti-Gal4 (green), anti-MSL1 (red) and counterstained with DAPI (blue). Gal4-MOF and MSL1 co-localize to many sites on the X chromosome (arrowhead) and autosomes in male nuclei (yellow, right panel). In female nuclei, Gal4-MOF binding is reduced to a few sites, the brightest of which corresponds to the location of the UAS-lacZ transgene (arrow). (B) Gal4-MOF co-localizes with MSL1 to many chromosomal sites in female nuclei that constitutively express MSL2.

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