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Figure 1 | BMC Molecular Biology

Figure 1

From: Regulation of PURA gene transcription by three promoters generating distinctly spliced 5-prime leaders: a novel means of fine control over tissue specificity and viral signals

Figure 1

Comparison of human (A) and mouse (B) PURA transcriptional start sites and 5' untranslated regions. Three distinct transcriptional start sites (TSSs) initiate transcription of human PURA. Human and mouse EST databases were utilized to determine TSSs of PURA. Numbering is from the A in the translationally- initiating ATG. A. TSS I - III are shown for humans. B. Two TSSs as determined from ESTs are shown for mouse. The one most distant from ATG has previously been identified [28]. The new mouse TSS is very homologous to human TSS III, which is verified in this report. Human transcripts starting at sites I and II are characterized by introns of dissimilar lengths, as indicated in A. The genomic locations of human and mouse PURA are given.

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BMC Molecular Biology

ISSN: 1471-2199

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