GENE | FC | FUNCTION | ||
---|---|---|---|---|
DYNC1I1 | 1.781 | Microtubule-based vesicular trafficking;retrograde axonal transport of signaling endosomes containing neurotrophins and associated downstream kinases | ||
HMGCS1 | 1.728 | Lipogenesis and biosynthesis of cholesterol | ||
BCL2 | 1.689 | Regulation of cell death and caspase activity; antiapoptotic | ||
CREB3L2 | 1.652 | Transcription factor of the CREB3 family; astrocyte proliferation in response to inflammation and trauma (gliosis) | ||
TRAF3IP2 | 1.558 | Activation of the transcription factor NFkB; implicated in malignant processes and in the regulation of the apoptotic response; mediates the antiapoptotic effect of TGF-beta and TNF-alpha | ||
ISLR2 | 1.544 | Integral membrane protein | ||
KLF6 | 1.544 | Zinc finger transcription factor; adipogenesis and inhibition of cellular growth | ||
PRICKLE1 | 1.508 | May regulate neurite formation during brain development | ||
ADIPOR1 | 1.504 | Component of the energy homeostatic mechanism; increases fatty acid oxidation and glucose uptake; may participate in the control higher brain functions | ||
PRSS3 | 1.498 | Encodes mesotrypsin, a brain-specific trypsin form thought to protect neural cells from apoptotic cell death |