Table 1 Proteins involved in interactions with cruciform structures

Junction-resolving enzymes

   Integrase family

RuvC

E.coli

[133–135]

Cce1

yeast

[136]

Ydc2

S.pombe

[134]

A22

Coccinia virus

[137]

Integrases

all

[119, 138]

   Restriction nuclease family

Endonuclease I

Phage T7

[139–141]

RecU

G+ bacteria

[134, 142]

Hjc, Hje

archea

[134, 143]

MutH

Eukaryotes

[25, 144]

   Other

Endonuclease VII

phage T4

[25, 145]

RusA

E.coli

[146]

MSH2

S. cerevisiae

[147, 148]

Mus81-Eme1

Eukaryotes

[42, 149–151]

TRF2

H. sapiens

[52, 152]

XPF, XPG protein families

Eukaryotes

[56, 153, 154]

Transcription, Transcription factors and DNA repair

PARP-1

H. sapiens and others

[51, 63]

BRCA1

H. sapiens and others

[49, 50, 91, 93]

P53

H. sapiens and others

[69, 73, 75, 76, 132, 155, 156]

Bmh1

S.cerevisiae

[35]

14-3-3

H. sapiens, S.cerevisiae

[34, 110]

Rmi-1

Yeast

[157]

Crp-1

S. cerevisiae

[158]

HMG protein family

all

[47, 159–161]

Smc

S. cerevisiae

[118, 162]

Hop1

S. cerevisiae

[163, 164]

ER estrogen receptor

mammals

[58]

Chromatin-associated proteins

DEK

mammals

[84, 85]

BRCA1

mammals

[49, 50, 91, 93]

HMG protein family

Eukaryotes

[47, 159–161]

Rad54

Eukaryotes

[48]

Rad51ap

Eukaryotes

[81]

Topoisomerase I

Eukaryotes

[101, 165]

Replication

S16

E.coli

[113]

GF14, homolog of 14-3-3

plants

[35]

MLL (leukemia)

H. sapiens

[125, 126]

WRN (Werner syndrome)

H. sapiens

[129]

AF10

H. sapiens

[114]

14-3-3

Eukaryotes

[34, 110]

DEK

mammals

[84, 85]

DNA-PK

Eukaryotes

[166]

Vlf-1

Baculovirises

[119]

HU

E. coli

[105, 167, 168]

Helicases (59, 44, and others)

all

[55]