Figure 4
From: Ste11p MEKK signals through HOG, mating, calcineurin and PKC pathways to regulate the FKS2 gene
Effect of mutations in PKC and calcineurin pathways and in CMK2 and PTK2 on Ste11ΔNp stimulation of reporter genes. STE11ΔN activation of FKS2 (-928 to +1)-lacZ (A), FKS2 (-706 to +1)-lacZ (B), PRM5-lacZ (C) and Δ-178 pCYC1-lacZ (D) in cell wall integrity and filamentous pathway mutants. STE11ΔN activation of FKS2 (-928 to +1)-lacZ (E), FKS2 (-706 to +1)-lacZ (F), PRM5-lacZ (G) and Δ-178 pCYC1-lacZ (H) in calcineurin pathway mutants. Data were expressed as mean ± SE of at least three independent experiments. Statistical significance was computed by the unpaired Student's t test. *p < 0.05, **p < 0.01.