Skip to main content
Figure 11 | BMC Molecular Biology

Figure 11

From: The leukemia associated nuclear corepressor ETO homologue genes MTG16 and MTGR1 are regulated differently in hematopoietic cells

Figure 11

Reporter gene analysis of the MTGR1 promoter. Functional analysis by sequential 5'-deletion. The 5'deleted MTGR1 reporter constructs -989 to +52 (-989), -656 to +52 (-656), -499 to +52 (-499), -308 to +52 (-302), -257 to +52 (-257), -207 to +52 (-257), and -145 to +52 (-145) were examined after expression in HEL cells. The transcriptional activity is retained by the -499 to +52 bp region indicating the location of the proximal MTGR1 promoter. The pGL3/basic and pGL3/SV40-promoter are used as negative and positive control, respectively in (A) and (B). The luciferase activity was normalized against pGL3/SV40-promoter activity and is shown for 3 to 5 separate transfections; bars represent the mean and the error bars show SEM.

Back to article page