Ribonomic analysis of human DZIP1 reveals its involvement in ribonucleoprotein complexes and stress granules

Table 1 Molecular and cellular functions associated with DZIP1 targets

Category^a	Top-ranked functions	Enrichment score
Binding function	Protein binding	28.69
	Nucleic acid binding	21.78
	Chromatin binding	4.37
Molecular function	Binding	23.48
	Catalytic activity	7.19
	Transcription regulator activity	3.2
	Molecular transducer activity	2.45
	Structural molecule activity	2.08
Components	Extracellular region	16.22
Components	Cell part	11.21
Associated network functions ^b	p- value	No. of molecules
Cell cycle	3.07E-12 - 4.89E-02	127
Gene expression	1.22E-10 - 4.65E-02	153
Cellular compromise	1.35E-10 - 2.95E-02	107
DNA replication, recombination, and repair	1.06E-09 - 3.61E-02	113
RNA posttranscriptional modification	7.52E-09 - 1.65E-02	44

^aGO annotations of DZIP1 mRNA targets.
^bIngenuity pathway analysis networks: Functions associated with the networks regulated by DZIP1.