Figure 8From: Important roles of multiple Sp1 binding sites and epigenetic modifications in the regulation of the methionine sulfoxide reductase B1 (MsrB1) promoterAnalysis of MsrB1 CpG island promoter methylation status in MCF7 and MDA-MB231 cells. Shown are results of bisulfite genomic sequencing of 20 individual clones. The x axis of the graph indicates the CpG doublet position in the 5'-flanking region of MsrB1 with respect to the start site of transcription; the y axis indicates the percentage of the subclones that were methylated.Back to article page