From: Mutational pattern and frequency of induced nucleotide changes in mouse ENU mutagenesis
 | Phenotype-based screens | Sequence-based screens | ||
---|---|---|---|---|
Mutation type | Â | Present study | Germ cells a | ES cells |
5' flanking | 0 | 1 | 1 | 0 |
Exonic | Â | Â | Â | Â |
   5' untranslated region | 2 | 0 | 1 | 0 |
   Missense | 175 | 44 | 45 | 18 |
   Make-sense | 2 | 1 | 1 | 0 |
   Nonsense | 46 | 3 | 4 | 0 |
   Synonymous | 0 | 17 | 15 | 9 |
   3' untranslated region | 0 | 1 | 2 | 0 |
Intronic b | 52 | 63 | 8 | 4 |
Not specified | 0 | 0 | 6 | 0 |
Total | 277 | 130 | 83 | 31 |