Fig. 6
From: Deciphering targeting rules of splicing modulator compounds: case of TG003
Groups with weak polypyrimidine tracts are more enriched with TG003 skip-enhanced exons. a Decision tree model of TG003 skip-enhanced exons. Boxes are colored according to their enrichment level with the color code shown at the bottom. b Bar graph of enrichment in the four groups of polypyrimidine tract strength in exons with short (length <65 nt), few splicing factor binding (ESE < 5 or 5 ≤ ESE < 16, ESS < 20). (*) indicates p value <0.05, and (**) p value <0.01, (***) p value <0.001, calculated by hypergeometric test