Fig. 3
From: Mice lacking microRNAs in Pax8-expressing cells develop hypothyroidism and end-stage renal failure
Dgcr8–Pax8Cre knockout animals develop end stage renal disesase. a Dgcr8 knockout mice develop severe renal failure as shown by increased serum urea (knockout n = 4, control n = 10; p < 0. 0005; error bars = SEM) and serum creatinine (knockout n = 4, control n = 10; p < 0. 0009; error bars = SEM) levels. b The kidneys of Dgcr8–Pax8Cre knockout mice weigh less than control kidneys (knockout n = 10, control n = 13; p < 0. 0001; error bars = SEM) but there is no significant difference in the kidney/body weight ratio between these groups