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Fig. 6 | BMC Molecular Biology

Fig. 6

From: Mice lacking microRNAs in Pax8-expressing cells develop hypothyroidism and end-stage renal failure

Fig. 6

Dgcr8Pax8Cre knockout kidneys show increased proliferation and apoptosis. a TUNEL staining reveals a massive upregulation of apoptosis in kidneys of Dgcr8 knockout mice (upper panel bar 200 µm; lower panel bar 50 µm, age of the mice 4–8 weeks). b and c An increase in proliferation is detectable especially in the cortex of Dgcr8 knockout kidneys (b bar 2 mm; c bar 100 µm)

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