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Fig. 11 | BMC Molecular Biology

Fig. 11

From: Properties of STAT1 and IRF1 enhancers and the influence of SNPs

Fig. 11

rs9260102 modulates IRF1 binding in vivo. a Chromosomal location of rs9260102 and the alleles (strong IRF1 binding in bold), and a genome browser view of the SNP, which lies upstream of HLA-A and within an IFNγ-induced IRF1 Chip-chip peak in HeLa cells. b ChIP-qPCR of basal and IFNγ-induced IRF1 recruitment at rs9260102 in GM18857 EBV transformed lymphocytes. c Electropherogram on left shows snapshot sequencing of ChIP DNA, with peak quantification plotted on the right (mean ± range, n = 2)

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