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Fig. 9 | BMC Molecular Biology

Fig. 9

From: Properties of STAT1 and IRF1 enhancers and the influence of SNPs

Fig. 9

Link between ISG responsiveness in HeLa cells, responsiveness in other cell types, and STAT1/IRF1 binding. a Percentage of ubiquitous (Ub), partially shared (pSh), or exclusive (Ex) human ISGs based on their responsiveness to IFNγ in the indicated number of cell lines. b Percentage of HeLa es-indISGs which respond in only HeLa or in more cell types (as in a). For full lists of ISGs and es-indISGs see Additional file 1: Tables S7, S8. c Level to which Ub, pSh or Ex es-indISGs are induced in HeLa cells. d Average number of TF binding at promoter (≤5 kb) and remote (>5 kb) sites of the indicated types of es-indISGs. Error bar indicates SEM; Asterisk p < 0.05, ANOVA followed by Fisher test

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