Skip to main content

Table 6 Genes regulated in the domoic acid (DA) induced grazer treatments that are involved or suggested to be involved in the biosynthesis of DA

From: Transcriptomic responses to grazing reveal the metabolic pathway leading to the biosynthesis of domoic acid and highlight different defense strategies in diatoms

Domoic acid

Accession number

Mean FC

Adjusted P value

Gene name

Description

Enzyme

EC:

In the methylerythritol phosphate metabolic pathway (MEP) to geranyl pyrophosphate (GPP)

 PSN0016235

1.88

< 0.001

Dxr

1-Deoxy-d-xylulose 5-phosphate reductoisomerase

1.1.1.267

 PSN0004050

1.82

< 0.001

ispH

4-Hydroxy-3-methylbut-2-enyl diphosphate reductase

1.17.1.2

 PSN0005356

1.61

0.043

ispG

4-Hydroxy-3-methylbut-2-en-1-yl diphosphate synthase

1.17.7.1

 PSN0002600

1.60

< 0.001

ispD

2-C-Methyl-d-erythritol 4-phosphate cytidylyltransferase, chloroplastic

2.7.7.60

 PSN0023754

1.60

0.013

ispE

4-Diphosphocytidyl-2-C-methyl-d-erythritol kinase

2.7.1.148

In the synthesis from MEP to GPP and l-glutamate towards domoic acid

 PSN0015669

12.23

< 0.001

DabB

Hypothetical protein

NA

 PSN0029114 + PSN002498

11.23

< 0.001

DabC

Dioxygenase

NA

 PSN0007588

9.41

< 0.001

DabA

N-prenyltransferase

NA

 PSN0005772

2.83

<0.001

idi1-2

Isopentenyl-diphosphate Delta-isomerase

5.3.3.2

 PSN0020364

2.83

< 0.001

DabD

Cytochrome P450

NA

Proline metabolism

 PSN0000830

1.67

< 0.001

P4HA

Prolyl 4-hydroxylase

1.14.11.2

 PSN0001687

1.62

0.002

NA

Ornithine cyclodeaminase

4.3.1.12

  1. Mean fold change (FC) and adjusted P values are based on three replicates