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Table 1 GO annotation for the down-regulated DEGs with potential MEF2A binding sites in the proximal promoter

From: MEF2A alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells

Category

Term

Count (%)

p-value

Fold enrichment

GAD_DISEASE_CLASS

Reproduction

8 (13.33)

0.03294

2.51

GAD_DISEASE_CLASS

Cardiovascular

21 (35)

0.03316

1.48

UP_KEYWORDS

Secreted

18 (30)

0.00002

3.14

UP_KEYWORDS

Disulfide bond

21 (35)

0.00097

2.10

UP_KEYWORDS

Signal

23 (38.33)

0.00181

1.90

UP_KEYWORDS

Glycoprotein

22 (36.67)

0.01248

1.66

UP_KEYWORDS

Cell junction

7 (11.67)

0.01257

3.56

UP_KEYWORDS

Cell membrane

16 (26.67)

0.03143

1.73

UP_KEYWORDS

Citrullination

3 (5)

0.03161

10.61

UP_KEYWORDS

Actin-binding

4 (6.67)

0.04397

5.01

UP_KEYWORDS

Thick filament

2 (3.33)

0.04765

40.35

UP_SEQ_FEATURE

Signal peptide

23 (38.33)

0.00012

2.30

UP_SEQ_FEATURE

Disulfide bond

19 (31.67)

0.00132

2.18

UP_SEQ_FEATURE

Zinc finger region:B box-type

3 (5)

0.01710

14.75

UP_SEQ_FEATURE

Glycosylation site:N-linked (GlcNAc.)

20 (33.33)

0.03095

1.58

UP_SEQ_FEATURE

Domain:B30.2/SPRY

3 (5)

0.03312

10.34